Striker Akinde has signed a loan deal from Bristol City until the end of the season but will miss out against Karl Robinson's men thanks to a slight groin strain.
Fellow new signing Marvin Morgan will continue his fledgling partnership in attack with Gavin Tomlin after Tomlin's goal gave John Still's men a surprise win at Hartlepool last weekend.
Midfielder Solomon Taiwo still has a hamstring problem. The on-loan Cardiff man is now back in full training but will not make Saturday.
Defender Will Antwi was back on the bench last week after a leg injury and will again be in the squad while striker Josh Scott has been admitted to hospital after failing to recover from a mystery virus.
Source: PA
Source: PA